ビス(トリフルオロメチル)フェニル基を有するステロイド化合物

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专利权人:

富士フイルム株式会社

发明人:

▲高▼橋 和信,相川 和広

申请号：

JP2006252511

公开号：

JP5053601B2

申请日:

2006.09.19

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide a compound having excellent solubility etc., and suitable for a lesion-selective liposome contrast medium.

SOLUTION: The compound is represented by general formula (I) [wherein, A represents an oxygen atom or a single bond L represents a bivalent linking group having a 1-10C main chain or a single bond A and L do not simultaneously represent the single bond and Ste represents a hydrocarbon group containing a steroid skeleton represented by general formula (II) as a partial structure] or a salt etc., thereof. Lesions of blood vessel can selectively be imaged by MRI (magnetic resonance imaging) imaging or PET (positron emission tomography) imaging using the contrast medium comprising a liposome containing the compound, a salt thereof, etc.

COPYRIGHT: (C)2008,JPO&INPIT

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中国工程科技知识中心

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