The present invention relates to a method for preventing or treating virus and protozoa infection in a subject in need thereof comprising: orally administering to said subject an effective amount of a composition comprising a complex consisting of a starch binding protein (SBP)-tagged immunostimulatory protein and a SBP-binding matrix, wherein the immunostimulatory protein is from Ganoderma species. The present invention also relates to a method for inducing interferon-gamma production in a subject in need thereof comprising: orally administering to said subject an effective amount of a composition comprising a complex consisting of a starch binding protein (SBP)-tagged immunostimulatory protein and a SBP-binding matrix, wherein the immunostimulatory protein is from Ganoderma species. The present invention further relates to a method for improving feed intake, growth rate or feed conversion ratio in a subject in need thereof comprising: administering to said subject by oral administration or injection an effective amount of a composition comprising a complex consisting of a starch binding protein (SBP)-tagged immunostimulatory protein and a SBP-binding matrix, wherein the immunostimulatory protein is from Ganoderma species.本發明係關於一種在有需要的對象中預防或治療病毒及原生動物感染的方法,包含:向該對象口服投予一有效量的組合物,該組合物包含一複合物,該複合物係由一帶有澱粉結合蛋白(SBP)標籤的免疫刺激蛋白及一SBP結合基質所組成,其中該免疫刺激蛋白係來自靈芝屬(Ganoderma)物種。本發明亦關於一種在有需要的對象中誘發干擾素-γ生產的方法,包含:向該對象口服投予一有效量的組合物,該組合物包含一複合物,該複合物係由一帶有澱粉結合蛋白(SBP)標籤的免疫刺激蛋白及一SBP結合基質所組成,其中該免疫刺激蛋白係來自靈芝屬(Ganoderma)物種。本發明進一步關於在有需要的對象中提高飼料攝取量,生長速率或降低飼料轉換率的方法,包含:向該對象口服或注射投予一有效量的組合物,該組合物包含一複合物,該複合物係由一帶有澱粉結合蛋白(SBP)標籤的免疫刺激蛋白及一SBP結合基質所組成,其中該免疫刺激蛋白係來自靈芝屬(Ganoderma)物種。
