ANTIBODY BINDING SITES SPECIFIC FOR EGFRvIII

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专利权人:

发明人:

申请号：

EP14758087.2

公开号：

EP3030581A1

申请日:

2014.08.07

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

This application describes binding proteins that specifically bind to EGFRvIII and multispecific binding proteins that specifically bind to EGFRvIII and CD3. Further described is a multispecific tandem diabody that binds to EGFRvIII and CD3. Further described are highly cytotoxic EGFRvIII/CD3 bispecific tandem diabody for recruiting T cells to specifically and potently kill several types of solid tumor cance

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