Henricus Jacobus Maria Gijsen,Adriana Ingrid Velter,Gregor James MacDonald,François Paul Bischoff,Tongfei Wu,Sven Franciscus Anna Van Brandt,Michel Surkyn,Mirko Zaja,Serge Maria Aloysius Pieters,Didie
申请号:
US13144554
公开号:
US08946426B2
申请日:
2010.02.02
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention is concerned with substituted bicyclic heterocyclic compounds of Formula (I)wherein Het1, Het2, A1, A2, A3 and A4 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.