THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.;The United States of America, as represented by the Secretary, Department of Health and Human Servic
发明人:
HENGLI TANG,EMILY M. LEE,WEI ZHENG,RUILI HUANG,MIAO XU,WENWEI HUANG,KHALIDA SHAMIM,GUOLI MING,HONGJUN SONG
申请号:
US16861281
公开号:
US20200289471A1
申请日:
2020.04.29
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention concerns the use of compounds and compositions for the treatment or prevention of Flavivirus infections, such as dengue virus infections and Zika virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus and Zika virus infection, by administering a compound or composition of the invention, to a subject in need thereof; methods for inhibiting Flavivirus infections, such as dengue virus and Zika virus infections, in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits useful for treating or preventing Flavivirus infections, such as dengue virus and Zika virus infections.