Compound of Formula Ia: ** Formula ** or a pharmaceutically acceptable salt thereof, in which: R1 is selected from the group consisting of: ** Formula ** R2 is H； R3 is -L3--OCH2CH2OCH3, -OCH2CH2CH3, -OCH2CH2CH2CH3, -Oi-butyl, -O-cyclobutyl, -O-cyclopentyl, cyclopropyl -OCH2-, -OCH 2 cyclobutyl, -OCH2CH2-cyclopropyl, -OCH2CH2CH2CH2OH, -OCH2CF3, -OCH2CH2CF3, - OCH2CH2CH2CF3 or (tetrahydrofuran-2-yl) methoxy； R10 is halogen, cyano, azido, nitro, alkyl, substituted alkyl, hydroxyl, amino, heteroalkyl or substituted heteroalkyl； and n is an integer from 0 to 4； wherein "alkyl" is a normal, secondary or tertiary hydrocarbon containing 1 to 20 carbon atoms； "heteroalkyl" refers to an alkyl group in which one or more carbon atoms have been replaced by a heteroatom selected from O, N or S； and "substituted" means having 1, 2 or 3 substituents selected from -X, -R, -O； >； = O, -OR, -SR, -S； -NR2, -N + R3,>； = NR, -CX3, -CN, -OCN, -SCN, -N>； = C>； = O, -NCS, -NO, -NO2,>； = N2, -N3, - NHC (>； = O) R, -C (>； = O) NRR -S (>； = O) 2O-； - S (>； = O) 2OH, -S (>； = O) 2R, -OS (>； = O) 2OR, -S (>； = O) 2NR, -S (>； = O) R, -OP (>； = O) (OR) 2, -P (>； = O) (OR) 2, -P (>； = O) (O-) 2, -P (>； = O) (OH) 2, -P (O) ( OR) (O-), -C (>； = O) R, -C (S) R, -C (O) OR, -C (O) O-, -C (S) OR, -C (O) SR, -C (S) SR, -C (O) NRR, -C (S) NRR, - C (>； = NR) NRR, where each X is independently F, Cl, Br, or I； and each R is independently alkyl.Compuesto de Fórmula Ia:**Fórmula** o una sal farmacéuticamente aceptable del mismo, en la que: R1 se selecciona entre el grupo que consiste en:**Fórmula** R2 es H； -L3-R3 es -OCH2CH2OCH3, -OCH2CH2CH3, -OCH2CH2CH2CH3, -O-i-butilo, -O-ciclobutilo, -O-ciclopentilo, -OCH2- ciclopropilo, -OCH2-ciclobutilo, -OCH2CH2-ciclopropilo, -OCH2CH2CH2CH2OH, -OCH2CF3, -OCH2CH2CF3, - OCH2CH2CH2CF3 o (tetrahidrofuran-2-il)metoxi； R10 es halógeno, ciano, azido, nitro, alquilo, alquilo sustituido, hidroxilo, amino, heteroalquilo o heteroalquilo susti
