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Improvements to matrix assisted laser desorption ionisation mass spectrometry imaging (maldi-msi)
专利权人:
SHEFFIELD HALLAM UNIVERSITY
发明人:
LEESA SUSANNE FERGUSON,ROSALIND WOLSTENHOLME,SIMONA FRANCESE
申请号:
GB201104365
公开号:
GB2489215B8
申请日:
2011.03.15
申请国别(地区):
GB
年份:
2013
代理人:
摘要:
A method of preparing a sample for matrix assisted laser desorption ionization mass spectrometry imaging analysis by a two-step process. Firstly, a MALDI matrix is dusted on to the sample followed by a spray of a suitable solvent onto the dusted sample. The present method has been successfully applied to the detection and mapping of several analyte classes in latent fingermarks. Using the present two-step method, fingermark enhancement, recovery and analysis from different substrate surfaces is now possible enabling visual and chemical information to be obtained simultaneously via remote testing.
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