JENSEN, SIMON SKJODE,ANDRESEN, THOMAS LARS,HENRIKSEN, JONAS ROSAGER,JOHANSEN, PIA THERMANN
申请号：
CA2867060
公开号：
CA2867060A1
申请日:
2013.03.14
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
This invention concerns a liposome comprising lipids and at least one active ingredient, wherein at least one of the lipids is a cationic lipid； said liposome exhibiting a net positive charge at physiological conditions at which said liposome preferentially adheres to monocytes in freshly drawn blood when compared to adherence to granulocytes, T-lymphocytes, B- lymphocytes and/or NK cells in freshly drawn blood, to a lipid-based pharmaceutical composition comprising said liposomes and their use in monocytic associated prophylaxis, treatment or amelioration of a condition such as cancer, an infectious disease, an inflammatory disease, an autoimmune disease or allergy.
