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Adhesive preparation
专利权人:
Hisamitsu Pharmaceutical Co.; Inc.
发明人:
Nakanishi, Masaru,Tsuruda, Kiyomi,Yamasoto, Shinji,Shoho, Kouki
申请号:
AU2007279643
公开号:
AU2007279643B2
申请日:
2007.08.01
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention provides an adhesive preparation comprising an elastic support and an adhesive layer laminated on at least one surface of the support. The elastic support is composed of a crimped woven fabric with stockinette stitch on both sides. The adhesive layer contains methyl salicylate in an amount of 10% by mass or more based on the total mass of the layer, and the water vapor transmission rate of the entire adhesive preparation measured at a temperature of 40°C and a relative humidity of 90% is 1 to 350 g/m⋅24hr. When the application amount of the adhesive layer is set to 50 to 300 g/m and the adhesive preparation is applied to the human skin for 8 hours such that the contact area is 280cm, the average ± standard deviation of AUC of the methyl salicylate in plasma is in the range of 3.0 to 60.0 ng⋅hr/mL, and the average ± standard deviation of AUC of salicylic acid being a metabolite of the methyl salicylate in plasma is in the range of 5000 to 13000 ng⋅hr/mL.
来源网站:
中国工程科技知识中心
来源网址:
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