David Eddington,Gerardo Mauleon,Joe Fu-jiou Lo,Megan Lynn Rexius,Jalees Rehman
申请号:
US13840570
公开号:
US20130295551A1
申请日:
2013.03.15
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A microfluidic device having a perfusion chamber, the perfusion chamber having a base, a bath opening in the base, a supply inlet and an exhaust outlet. The device further includes a gas permeable membrane attached beneath the perfusion chamber, the gas permeable membrane having a first opening in registration with the supply inlet and a second opening in registration with the exhaust outlet. A substrate is attached to the gas permeable membrane, the substrate having at least one microchannel arranged for flow communication with the supply inlet and the exhaust outlet. In addition, a slide is attached to the substrate. As such, gas introduced through the supply inlet is communicated to the microchannel via the first opening, and the gas permeable membrane is positioned to be exposed to the gas to communicate the gas to the bath opening.