Shlomo Dagan,Rachel Eren,Hemant Kumar Misra,Walter G. Gowan, Jr.,Sandra OConnor
申请号:
US12821593
公开号:
US08580256B2
申请日:
2010.06.23
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides liquid formulations of antibodies or fragments thereof that specifically bind to a hepatitis B virus (HBV) antigen, which formulations exhibit stability, low to undetectable levels of aggregations, and very little to no loss of the biological activities of the antibodies or antibody fragments, even during long periods of storage. Furthermore, the invention provides methods of preventing, treating or ameliorating one or more symptoms associated with HBV infection utilizing the liquid formulations of the present invention.