The present invention provides for methods of producing a drug product that is capable of providing controlled and sustained release of a drug. Particularly, the release of the drug will be to a specific tissue area in the body. The methods include, but are not limited to, providing an impermeable casing with an open end, placing a compressed drug pellet into the impermeable casing, coating the open end of the impermeable casing with a permeable layer to create a release window for the drug product to provide controlled and/or sustained release of the drug.
