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OPTIMISATION DE LA CLAIRANCE DE MOLÉCULES LIÉES À DES PROTÉINES EN UTILISANT UN TRAITEMENT DE FILTRATION EN CASCADE
专利权人:
LTD.;NIKKISO CO.
发明人:
申请号:
EP08841705.0
公开号:
EP2227268B1
申请日:
2008.10.15
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
A hemofiltration system or method removes unwanted molecules from a flow of blood using cascaded first and second hemofilters. Filtration of the blood in first hemofilter raises hemoconcentration of unwanted protein-bound molecules. Combination of a substitution fluid with outflow from the first hemofilter creates a concentration differential between bound and unbound molecules that frees unwanted molecules from protein bonds. Filtration of the combined fluids in a second hemofilter removes the unwanted free molecules. A second substitution fluid may be added to the twice filtered blood fluid for return to a patient. Removal of inflammatory mediators, apoptotic mediators, and certain electrolytes may be effected, and the removal may be optimized by controlling fluid flows and transmembrane pressures.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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