The present invention relates to a composition for removing substances causing sick house syndrome, and a removal method of the substances causing sick house syndrome. The composition of the present invention removes the substances causing sick house syndrome using chitosan and cyclodextrin, thereby being environmentally-friendly; has excellent harmful substance removal efficiency, and has excellent antibacterial and deodorizing effects.본 발명은 새집증후군 유발물질 제거용 조성물 및 이를 이용한 새집증후군 유발물질 제거방법에 대한 것으로, 키토산과 사이클로덱스트린을 활용하여 새집증후군 유발물질을 제거함에 따라 친환경적이며, 유해물질 제거 효과가 뛰어나고, 항균 및 소취효과가 우수하다.