Christiaan Peter Maria Reutelingsperger;Peter Jozef Jacobus Moonen
发明人:
Christiaan Peter Maria Reutelingsperger,Peter Jozef Jacobus Moonen
申请号：
US13060667
公开号：
US08747808B2
申请日:
2009.08.26
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A radiolabeled annexin comprising at least 2 up to 20 histidine residues at its N-terminus is disclosed. At least two of said histidine residues are adjacent or separated by no more than one other amino acid. The radiolabeled annexin is a stable complex with a radionuclide such as technetium 99m. The radiolabeled annexin can be used in a method of imaging cell death in a nucleated cell within a region of a mammalian subject in vivo.
