Use of MVA or MVADELTAE3L as immunotherapeutic agents against solid tumors

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专利权人:

Memorial Sloan Kettering Cancer Center

发明人:

Deng, Liang,Wolchok, Jedd,Merghoub, Taha,Shuman, Stewart,Dai, Peihong,Wang, Weiyi

申请号：

AU2016249521

公开号：

AU2016249521A1

申请日:

2016.04.18

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The present disclosure relates to modified vaccinia Ankara (MVA) virus or MVAAE3L delivered intratumorally or systemically as an anticancer immunotherapeutic agent, alone, or in combination with one or more immune checkpoint blocking agents for the treatment of malignant solid tumors. Particular embodiments relate to mobilizing the host's immune system to mount an immune response against the tumor.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/