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COMBINED DRUG FOR USE AS A MEDICINAL PRODUCT
专利权人:
СиБиТи ДЕВЕЛОПМЕНТ ЛИМИТЕД (GB)
发明人:
РИЧАРДСОН Питер (GB)
申请号:
RU2012104552/15
公开号:
RU2012104552A
申请日:
2010.07.09
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A combined preparation containing an adenosine receptor agonist A and a calcium channel blocker. 2. The combined preparation according to claim 1 for co-administration or sequential administration of an adenosine receptor agonist A and a calcium channel blocker to a subject. A combination preparation according to claim 1 or 2, which comprises a pharmaceutically acceptable carrier, excipient or diluent. The combined preparation according to claim 1 for use as a medicine. The combination preparation according to claim 1 for the prevention, treatment or alleviation of a pathological condition that can be prevented, cured or alleviated by an adenosine receptor agonist A.6. The combined preparation according to claim 1 for the prevention, treatment or relief of pain, inflammation, cancer, autoimmune disease, ischemic reperfusion injury, epilepsy, sepsis, septic shock or neurodegeneration. The combination preparation of claim 1 for the prevention, treatment or alleviation of microvascular complications of diabetes, including diabetic neuropathy, diabetic neuropathic pain, diabetic skin ulcers and dermopathy, diabetic kidney disease or diabetic retinopathy. The combination preparation according to claim 1, wherein the adenosine receptor agonist A contains a compound of formula (I): wherein R is Salkoxy and X is OH or H; or a pharmaceutically acceptable salt thereof. 9. The combination preparation of claim 8, wherein the adenosine receptor agonist A contains spongosin. The combined preparation according to claim 1, wherein the adenosine receptor agonist A contains a compound of any of the following formulas (II) to (VII) :( II) where if X = OH, then R stands for Cu1. Комбинированный препарат, содержащий агонист аденозинового рецептора Aи блокатор кальциевых каналов.2. Комбинированный препарат по п.1 для совместного введения или последовательного введения субъекту агониста аденозинового рецептора Aи блокатора кальциевых каналов.3. Комбинированный препарат по п.1 или 2, ко
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