Refers to an isolated monoclonal antibody that binds to an epitope of the inhibitor of Human Tissue factor Pathway (SEC ID number: 1), which includes the remains of the epitope of Kunitz Domain 1 selected from the group of asp31, asp32, gly33, among others, and the remains of the Kunitz Domain 2 Selected from the group consisting glu100, glu101, ASP 102, among others.It also relates to a Pharmaceutical composition that is useful for the treatment of Genetic and acquired defects of coagulation such as Hemophilia A and B.SE REFIERE A UN ANTICUERPO MONOCLONAL AISLADO QUE SE UNE A UN EPITOPO DEL INHIBIDOR DE LA RUTA DEL FACTOR TISULAR HUMANO (SEC ID N�:1), EN EL QUE DICHO EPITOPO COMPRENDE LOS RESTOS DE DOMINIO DE KUNITZ 1 SELECCIONADOS DEL GRUPO DE Asp31, Asp32, Gly33, ENTRE OTROS, Y LOS RESTOS DEL DOMINO KUNITZ 2 SELECCIONADOS DEL GRUPO QUE CONSISTE EN Glu100, Glu101, Asp 102, ENTRE OTROS. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA QUE ES UTIL PARA EL TRATAMIENTO DE DEFECTOS GENETICOS Y ADQUIRIDOS DE LA COAGULACION TALES COMO LA HEMOFILIA A Y B.
