James D. Weiland;Francis S. Markland, Jr.;Mark S. Humayun;Atoosa Lotfi;Adrian P. Rowley;Lucien D. Laude
发明人:
Adrian P. Rowley,Lucien D. Laude,Mark S. Humayun,James D. Weiland,Atoosa Lotfi,Francis S. Markland, Jr.
申请号：
US12041651
公开号：
US08852290B2
申请日:
2008.03.03
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention provides a biocompatible silicone implant that can be securely affixed to living tissue through interaction with integral membrane proteins (integrins). A silicone article containing a laser-activated surface is utilized to make the implant. One example is an implantable prosthesis to treat blindness caused by outer retinal degenerative diseases. The device bypasses damaged photoreceptors and electrically stimulates the undamaged neurons of the retina. Electrical stimulation is achieved using a silicone microelectrode array (MEA). A safe, protein adhesive is used in attaching the MEA to the retinal surface and assist in alleviating focal pressure effects. Methods of making and attaching such implants are also provided.
