NORTH AMERICAN PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME (PRRS) VIRUS AND USES THEREOF农业专利-农业学术服务平台

发明人:: CALVERT, JAY GREGORY,卡尔佛特杰葛雷高瑞,卡爾佛特傑葛雷高瑞,WELCH, SIAO-KUN WAN,威尔奇赛欧昆万,威爾奇賽歐昆萬,SLADE, DAVID EWELL,史莱德大卫艾威尔,史萊德大衛艾威爾

摘要：: The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, methods to make it and related polypeptides, polynucleotides, and various components. Vaccines comprising the genetically modified virus and polynucleotides and a diagnostic kit to distinguish between naturally infected and vaccinated animals are also provided.本發明提供經分離之聚核苷酸分子,其包含編碼感染性RNA序列之DNA序列,該感染性RNA序列編碼經遺傳修飾之北美PRRS病毒,其製造方法,及相關多肽、聚核苷酸及各種組分。亦提供包含經遺傳修飾之病毒及聚核苷酸的疫苗,及辨別天然感染動物及疫苗接種動物之診斷套組。