A pharmaceutical composition comprising antioxidants and phenolic compounds. The pharmaceutical composition includes oleuropein, hydroxytyrosol (3′；4′；-DHPEA) and tyrosol (p-DHPEA) and flavomoids, such as, without limiting, rutin, quercetin, luteolin and apigenin. The pharmaceutical composition further includes caffeic acid. The pharmaceutical composition further includes oleocanthal (p-DHPEA-EDA). The pharmaceutical composition wherein oleuropein is present from about at least 30%, hydroxytyrosol from about at least 50%, tyrosol from at least about 25%, and oleocanthol from at least about 2%, and suitable pharmaceutical excipients.
