The present invention is to close a kind of regulation method of the pore size of bacteria cellulose of what, including that will have an oil-in-water microemulsion or microcapsules addition one Bacteria Culture liquid media of what in oily phase particle dispersion what water phase, what is that the oil phase particle or microcapsules are swum on the Bacteria Culture liquid media； And the bacterium under substantially static and atmospheric condition in the Bacteria Culture liquid media forms sheet bacteria cellulose at gas and liquid surface, is wherein dispersed with the oil phase particle or microcapsules inside the sheet bacteria cellulose. The present invention also discloses a kind of purposes that material is applied using the bacteria cellulose what preparation wound of the pore size with regulation.本發明是關於一種細菌纖維素的孔隙大小的調控方法，包括將具有油相粒子分散於水相中的一水包油微乳液或微膠囊添加於一細菌培養液態媒體，於是該油相粒子或微膠囊漂浮在該細菌培養液態媒體上；及在實質上靜止及大氣狀態下該細菌培養液態媒體中的細菌在氣體及液體界面處形成片狀細菌纖維素，其中該片狀細菌纖維素內部分散有該油相粒子或微膠囊。本發明亦揭示一種利用具有調控的孔隙大小的細菌纖維素於製備創傷敷材的用途。
