作為RIPK2抑制劑之吡啶及吡嗪化合物农业专利-农业专业知识服务系统

发明人:: CUI, JIANWEN,崔剑文,崔劍文,GAO, DONGHONG AMY,高　东红,高　東紅,LIU, PINGRONG,刘苹蓉,劉苹蓉,MCKIBBEN, BRYAN PATRICK,麦克奇班　布莱恩　派崔克,麥克奇班　布萊恩　派崔克,MILLER, CRAIG ANDREW,米勒　克莱格　安德鲁,米勒　克萊格　安德魯,RAZAVI, HOSSEIN,拉札维　贺斯因,拉札維　賀斯因,SPEN,高东红,高東紅,麦克奇班布莱恩派崔克,麥克奇班布萊恩派崔克,米勒克莱格安德鲁,米勒克萊格安德魯,拉札维贺斯因,拉札維賀斯因

摘要：: The present invention relates to compounds of formula (I):or pharmaceutically acceptable salts thereof, wherein R1, R2, X, Y, and HET are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.本發明係關於式(I)之化合物，或其醫藥學上可接受之鹽，其中R1、R2、X、Y及HET如本文所定義。本發明亦關於包含此等化合物之醫藥組合物、將此等化合物用於治療各種疾病及病症之方法、製備適用於此等方法之此等化合物及中間物的方法。