Hete rocyclic derivatives and its application in neurogenic disease treatment农业专利-农业学术服务平台

发明人:: S．巴迪格,M．舍布罗鲁,M．舍布羅魯,K．胡尔特,K．胡爾特,S．雅基耶,R．M．吕尔恩德,R．M．呂爾恩德,R．马绍尔,R．馬紹爾,H．鲁伊格尔,H．魯伊格爾,M．廷特尔诺特布洛莱伊,M．廷特爾諾特布洛萊伊,S．J．费恩施塔尔,S．J．費恩施塔爾,M．沃格特勒,S.巴迪格,M.舍布罗鲁,M.舍布羅魯,K.胡尔特,K.胡爾特,S.雅基耶,R.M.吕尔恩德,R.M.呂爾恩德,R.马绍尔,R.馬紹爾,H.鲁伊格尔,H.魯伊格爾,M.廷特尔诺特布洛莱伊,M.廷特爾諾特布洛萊伊,S.J.费恩施塔尔,S.J.費恩施塔爾,M.沃格特勒

摘要：: This Hair is bright to be related to formula (I) Miscellaneous Ring compound, in formula (I), all Change amounts are as illustrated to determine Righteousness in Books； the bright It of this Hair is related to its Drug and Group is used to close object, its Group conjunction product and its Men as the purposes of Drug object, and special Do what leads to the purposes that Over inhibits BACE-1 or BACE-2 and controls Treatment Ah Seoul Ci Haimo disease or diabetes.本發明涉及式(I)雜環化合物，在式(I)中，所有的變量均如說明書中所定義，本發明還涉及其藥用組合物、其組合産品以及它們作爲藥物的用途，特別用於通過抑制BACE-1或BACE-2而治療阿爾茨海默病或糖尿病的用途。