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具有(1E,6E)-1,7-雙-(3,4-二甲氧基苯基)-4,4-二取代的庚-1,6-二烯-3,5-二酮結構骨架的化合物、它們的生物活性及其用途
专利权人:
ANDROSCIENCE CORPORATION
发明人:
SHIH, CHARLES C,SHI, QIAN,WANG, HUI-KANG,‧石,史謙,王慧康
申请号:
HK15112031.9
公开号:
HK1211211A
申请日:
2015.12.07
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl)-propenal moiety. The compounds and compositions of the present invention are useful in the treatment or prevention of medical conditions including androgen associated conditions, androgen associated inflammation, a wound (the compounds assist with wound healing), acne, rheumatoid arthritis, psoriasis, rosacea, and alopecia; Kennedy's disease (spinal and bulbar muscular atrophy, or SBMA), polyglutamine-mediated motor neuron degeneration; cancer such as prostate cancer, bladder cancer, breast cancer, ovarian cancer, hepatocellular (liver) cancer, and pancreatic cancer; and other medical conditions described herein. Treatment of such medical condition includes administering to an individual suffering from a medical condition describe herein, a therapeutically effective amount of any of the disclosed compounds, their derivatives, or pharmaceutical compositions thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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