PROBLEM TO BE SOLVED: To provide a composition which enables the more effective development of the efficacy of a water-soluble drug in a solution containing the drug； and a dispersion in which a hydrophobic drug can be dispersed stably without requiring the use of any surfactant.SOLUTION: Disclosed is a composition comprising ultra-fine bubbles having a mode particle size of 500 nm or less, a drug and water, where the number of the ultra-fine bubbles is 1,000,000 or more per 1 ml.【課題】水溶性薬剤を含む溶液において薬剤の効果をよりよく発現させる組成物を提供すること。また界面活性剤を使用することなく疎水性薬剤を安定に分散させた分散体を提供すること。【解決手段】最頻粒子径が５００ｎｍ以下である超微細気泡と薬剤、および水を含み、前記超微細気泡が１ｍｌ当たり１００万個以上存在する、組成物。【選択図】 図１
