ANTICORPS BISPECIFIQUE A FORME HETERODIMERE DE TYPE SIMILAIRE A UNE STRUCTURE D'ANTICORPS NATUREL ANTI-PD-1/ANTI-VEGF ET PREPARATION ASSOCIEE

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专利权人:

BEIJING HANMI PHARMACEUTICAL CO.; LTD.

发明人:

YANG, YAPING,SONG, NANMENG,XIAO, WENCHU,LI, ZHENLEI,ZHANG, LINA,GU, MINGYUE,ZHAN, CHUNGUANG,LIU, JIAWANG,KIM, MAENGSUP

申请号：

CA3090878

公开号：

CA3090878A1

申请日:

2019.02.02

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

An anti-PD-1/anti-VEGF natural antibody structure-like heterodimeric form bispecific antibody and the preparation thereof. Provided are a highly stable, heterodimeric form anti-PD-1/anti-VEGF bispecific antibody having natural IgG characteristics and free of mismatched heavy and light chains and a preparation method for the antibody. The bispecific antibody is capable of simultaneously binding with two target molecules and provides improved efficacy in treating a complicated disease.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/