A closed suction cleaning system includes an interface coupled to a main body inlet of a multi-port tube-connector assembly for coupling to an endotracheal tube. A catheter main body includes a distal inflatable element positioned along a distal end portion of the catheter main body. An input module is located at a proximal end of the catheter main body. The input module includes a flow regulator with a mechanical user control element. In a first configuring step, the flow regulator simultaneously regulates suction through the catheter main body and inflation of the distal inflatable element. After a second configuring step, the flow regulator and mechanical user control element may regulate suction through a suction lumen but not cause inflation of the distal inflatable element. A pliable sleeve inhibits contamination of a portion of the catheter main body from an external environment.
