HILL Oliver,GIEFFERS Christian,THIEMANN Meinolf,BUCHANAN Fritz G.,PHILLIPS Darren C.,LAPPE Susan E.
申请号：
SI201530223
公开号：
SI3134430T1
申请日:
2015.04.23
申请国别(地区):
SI
年份:
2018
代理人:
摘要：
Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
