INHIBITEURS D'HISTONES DEMETHYLASES

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专利权人:

INC.;GILEAD SCIENCES

发明人:

LABELLE, MARC,BOESEN, THOMAS,ZHANG, RUI,MARTYR, CUTHBERT D.,SARASWAT, NEERJA

申请号：

CA2943824

公开号：

CA2943824A1

申请日:

2015.03.30

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

Compounds of the form in which Q is selected from -COOH -CH=NR12, -W, -CH2NHR13, -CH=0 and -CH(OR17)2 capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer and formulations and methods of use of such compounds.

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