WALLING, JOHN,PARENT, STEPHAN,JONAITIS, DAVID,KRAL, ROBERT
申请号：
AT08795303
公开号：
AT549035T
申请日:
2008.08.14
申请国别(地区):
AT
年份:
2012
代理人:
摘要：
A triterpenoid compound, methyl 2-cyano-3,12-dioxo-Ieana- 1,9(11)-dien-28-oate (CDDO methyl ester), has a crystalline, glassy solid form and a non-hydrous crystalline form that can prepared, for example, from a saturated methanol solution. The glassy form displays an enhanced bioavailability over the non-hydrous crystalline form. Each form of CDDO methyl ester is a superior candidate for use, typically in solid dosage form, for treating a variety of disease states, generally associated with inflammation.
