Merck Sharp & Dohme Corp.;Alectos Therapeutics, Inc.
发明人:
Kaul, Ramesh,McEachern, Ernest J.,Mu, Changwei,Selnick, Harold G.,Vocadlo, David J.,Wang, Yaode,Wei, Zhongyong,Zhou, Yuanxi,Zhu, Yongbao
申请号：
AU2011349021
公开号：
AU2011349021B2
申请日:
2011.12.21
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The invention provides compounds with enhanced permeability for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc.
