To provide a cancer treatment agent and a cancer treatment method having stronger therapeutic effects on various types of cancer than those of conventional chemotherapy.SOLUTION: The present inventors have conducted intensive studies to search for an agent that can enhance therapeutic effects of an anticancer agent by combination with an anticancer agent and, as a result, find out that a combination of caffeine citrate and an anticancer agent synergistically improves therapeutic effects of the anticancer agent.SELECTED DRAWING: None【課題】様々な癌種において、従来の化学療法よりも強力な治療効果を有する癌治療剤及び癌治療方法を提供する。【解決手段】抗癌剤と組み合わせることで抗癌剤の治療効果を増強できる薬剤を鋭意検討した結果、「カフェインクエン酸塩と抗癌剤との組み合わせが、抗癌剤の治療効果を相乗的に高めること」を見出した。【選択図】なし