DR JAYANT DESHPANDE,SUBHRANGSU SENGUPTA,PRAVIN NALAWADE,SWAPNIL KHAMBORKAR
申请号：
IN1660/MUM/2014
公开号：
IN2014MU01660A
申请日:
2014.05.16
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
The instant invention provides hydrophilic matrix beadlet compositions comprised of at least one fat soluble nutrient and effective amount of cellulose polymer with low viscosity. The invention also provides a process for the preparation of the said hydrophilic matrix composition by employing fluid bed system or extrusion spheronization technique. This hydrophilic matrix beadlet composition is comprised of at least 5% to about 25% carotenoid wherein free lutein is present in combination with zeaxanthin. The free flowing nature of said composition allows it to be compressed into tablets or to be filled into two piece capsules or blend as dry premix for beverage applications. These hydrophilic matrix compositions exhibit desired dissolution characteristics and at least 1.6 times more bioavailability as compared with the marketed reference formulations containing modified starch, thus making it advantageous for nutraceutical applications.
