Provided are pharmaceutical compositions comprising glycopyrrolate, a beta2-adrenergic agonist, and optionally a corticosteroid. Exemplified beta2-adrenergic agonists include indacaterol, formoterol, vilanterol, carmoterol and olodaterol. Exemplified corticosteroids include fluticasone and mometasone. The compositions can be used in the treatment of respiratory, inflammatory or obstructive airway diseases.