The present application relates to variants of anti-IL-17A / F antibodies, in particular glycosylation variants, charge variants, acid variants, HMWS variants, reduction-resistant cross-linking variants, and anti-IL-17A / F antibodies and their It relates to compositions comprising the variant (s), methods of making the compositions, methods of characterization, and methods of use. [Selection figure] None本出願は、抗IL-17A/F抗体の変異体、特にグリコシル化変異体、電荷変異体、酸性変異体、HMWS変異体、耐還元性架橋変異体、ならびに抗IL-17A/F抗体及びその変異体(複数可)を含む組成物、その組成物を作製する方法、特徴付ける方法、及び使用する方法に関する。【選択図】なし