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Pyrido [2, 3-B] pyrazine compounds and their therapeutical uses such as for inhibiting ATP consuming proteins and treating diseases associated therewith
专利权人:
Alfred Jonczyk;Frank Zenke;Guenter Hoelzemann;Dieter Dorsch;Christiane Amendt
发明人:
Dieter Dorsch,Alfred Jonczyk,Guenter Hoelzemann,Christiane Amendt,Frank Zenke
申请号:
US14002991
公开号:
US09051318B2
申请日:
2012.02.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to novel pyrido[2,3-b]pyrazine compounds of formula (I):and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors.
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