Shih, David Q.,Targan, Stephan R.,Li, Dalin,Bilsborough, Janine
申请号:
AU2014241162
公开号:
AU2014241162A1
申请日:
2014.03.27
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The invention relates to methods of treating fibrosis and inflammatory bowel disease. In one embodiment, the present invention treats gut inflammation by administering a therapeutically effective dosage of TL1A inhibitors and/or DR3 inhibitors to an individual. In another embodiment, the present invention provides a method of reversing tissue fibrosis in an individual by inhibiting TL1A-DR3 signaling function.