JUNG SUNG YOUB,JANG MYUNG HYUN,SHEN LING AI,PARK YOUNG KYUNG,KWON SE CHANG
申请号：
ARP120102030
公开号：
AR086866A1
申请日:
2012.06.07
申请国别(地区):
AR
年份:
2014
代理人:
摘要：
This paper introduces the different activities of a glucose type peptide-1 receptor and a glucose receptor, including the prevention or treatment of obesity, including peptides as active ingredients. Different from the local oxygen modulation, the peptide in the present application can reduce food intake, remove gastric space, and promote lipolysis with low side effects, and has strong receptor activation effect. So,se puede usar de manera generalizada en un tratamiento seguro y eficaz de la obesidad Reivindicaci n 1 Un p ptido caracterizado porque comprende una secuencia de amino cidos de acuerdo con la f rmula (1) R1-X1-X2-GTFTSD-X3-X4- B-hydroxidatzopropionilo, 4-imidazoacetilo, b-carboxi imidazopropionilo o tirosina； X1 es AIB (aminosobutirico acid)；d-alanina glicina Sar (N-metilglicina)SERINA or d-serina； X2 is glutamate or glutamic acid； X3 is leukemia or thyroid； X4 is SERINA or alanina； X5 is lysine or arginine； X6 is glutamate or thyroid； X7 is leukemia or thyroxine； X8 is aspirin or glutamate； x9 is glutamate, SERINA or a-methyl-glutamate, or has been removed； X10 is glutamate, Glutamic acid, lysine, amino acid, amino acid or SERINA, or have been deleted； X11 is alachlor, aminoning or diazepam, or has been deleted； X12 is alachlor, aminoning, SERINA or valina, or has been deleted； x13 is lysine, glutamic acid, amino acid or formic acid glutamate, or has been deleted； x14 is aspirin, glutamate or leukemia,Or has been deleted； x15 is phenylacetamide or has been deleted； x16 is isofluorooctanoic acid or diazepam, or has been deleted； x17 is alanina, cisteine, glutamic acid, lysine, glutamic acid or methylpropionic acid, or has been deleted； x18 is triptopheno or has been deleted； X19 is alanina, isofluorooctanoic acid, leucina, SERINA or valina, Or deleted； X20 is alachlor, lysine, thyroxine, glutamic acid or aminoning, or deleted； X21 is asparagine or deleted； X22 is alachlor, glycerin or Trinitro, or deleted； x23 is crocin or lysine, or deleted； x24 is a pe
