A contact-free method of determining biometric parameters and physiological parameters of a subject of interest (20) to be examined by a medical imaging modality (10), comprising steps of taking (72) a picture by a first digital camera (52) including a total view of an examination table (44)； applying (74) a computer vision algorithm or an image processing algorithm to the picture for determining a biometric parameter of the subject of interest (20) in relation to the examination table (44)； taking (78) at least one picture with a second digital camera (58), whose field of view (60) includes a region of the subject of interest (20) that is related to the at least one determined biometric parameter； using data indicative of the determined biometric parameter to identify (82) a subset of pixels of the at least one picture taken by the second digital camera (58) that define a region of interest (64) from which at least one physiological parameter of the subject of interest (20) is to be determined, taking (84) a plurality of pictures of the region of the subject of interest (20) with the second digital camera (58), and applying (86) a computer vision algorithm or an image processing algorithm to pictures of the plurality of pictures taken by the second digital camera (58) for calculating the region of interest (64) in the pictures of the plurality of pictures for determining the physiological parameter of the subject of interest (20) during examination； a camera system (50) for determining, in a contact-free way, biometric parameters and physiological parameters of a subject of interest (20) to be examined by use of a medical imaging modality (10) and using such method； and—a medical imaging modality (10) configured for acquisition of scanning data of at least a portion of a subject of interest (20), the medical imaging modality (10) comprising such camera system.
