The invention relates to a device for establishing and maintaining a sterile environment for conducting surgical procedures. In particular, the invention is related to a tent-like device providing an interior space and being attachable to a patient's skin to allow surgical treatment of the patient. Several aspects of the invention are directed to devices to be used in connection with such a surgical procedure using the tent-like device. According to the invention, an Isolation device for providing a sterile Operation Chamber above a skin region of a patient is provided, in particular for performing a surgical procedure, said Isolation device comprising an inflatable bag coupled to a support frame, the support frame having a transport configuration and an Operation configuration, wherein in the transport configuration, the first inflatable bag is confined, such as to have compact dimensions； in the Operation configuration, the first inflatable bag is extended, such as to form said sterile Operation Chamber.
