The Board of Trustees of the Leland Stanford Junior University
发明人:
K. Christopher Garcia,Darren L. Bates,Ignacio Moraga
申请号：
US15662180
公开号：
US20180016316A1
申请日:
2017.07.27
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed herein are IL-4 cytokine compositions with enhanced biological activity having increased selectivity for IL-4 cytokine receptors, and methods for their use. These compositions encompass interleukin-4 (IL-4) muteins. The disclosed methods encompass administering an IL-4 to treat neoplastic diseases, autoimmune diseases, infectious diseases or for expanding a hematopoietic cell population.
