Per-Göran Gillberg,Jan Mattsson,Ingemar Starke,Santosh S. Kulkarni
申请号：
US16508125
公开号：
US20190367467A1
申请日:
2019.07.10
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention relates to 1,5-benzothiazepine and 1,2,5-benzothiadiazepine derivatives of formula (I). These compounds are bile acid modulators having apical sodium-dependent bile acid transporter (ASBT) and/or liver bile acid transport (LBAT) inhibitory activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment of cardiovascular diseases, fatty acid metabolism and glucose utilization disorders, gastrointestinal diseases and liver diseases.
