<;P>;PROBLEM TO BE SOLVED: To provide a pharmaceutical composition, etc., comprising an &alpha; antigen, etc., integrated into a PIV2 (parainfluenza virus type 2) and usable for therapy/prophylaxis of allergic diseases. <;P>;SOLUTION: The pharmaceutical composition is obtained by integrating a gene encoding the &alpha; antigen derived from an acid-fast bacterium (e.g. Mycobacterium kansasii) (antigen 85 complex constituent protein 85B), an analog thereof (85A or 85C, etc.) or a mutant having similar actions thereto into the PIV2 in which an M protein is deficient. <;P>;COPYRIGHT: (C)2008,JPO&INPIT