PROBLEM TO BE SOLVED: To provide a compound having an AMP-activated protein kinase (AMPK) activation function, exhibiting an effect originated from an AMPK activation function in living bodies, and usable, for example, as a lipid decreasing agent, a preventive or therapeutic medicine for arterial sclerosis, a preventive or therapeutic medicine for diabetes, a preventive or therapeutic medicine for obesity, and a therapeutic medicine for cancers.SOLUTION: The compound is a benzyl parabanate derivative represented by formula (1), a pharmaceutical acceptable salt thereof or a hydrate thereof.COPYRIGHT: (C)2013,JPO&INPIT【課題】AMP-activated protein kinase(AMPK)活性化作用を有し、かつ生体内においてAMPK活性化作用に由来する効果を示す、例えば脂質低下剤、動脈硬化の予防あるいは治療薬、糖尿病薬の予防あるいは治療薬、肥満の予防あるいは治療薬、癌治療薬として使用できる化合物の提供。【解決手段】下記一般式(1)で表されるベンジルパラバン酸誘導体もしくはその薬理上許容される塩またはそれらの水和物。【選択図】なし
