New bite-activated dental hygiene devices are provided. In one aspect, a high-speed tooth-cleaning device is provided, which is configured to be bitten down on by a user and which, when properly positioned, scrubs and flosses all of the users teeth at once, without user-driven brushing. In other aspects of the invention, a device comprises bite-actuated tooth- and gum-brushing channels and other features facilitating the variable bite-actuated release and application of a dentifrice and scrubbing.