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METHODS OF TREATING CANCER USING ANTIBODIES AND MOLECULES THAT IMMUNOSPECIFICALLY BIND TO BTN1A1
专利权人:
INC.;STCUBE &; CO.
发明人:
Stephen Sunghan Yoo,Yong-Sik Bong,Kyu Lee Han,Michael Joseph Surace
申请号:
US16618050
公开号:
US20200131266A1
申请日:
2018.05.30
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are methods for treating cancer using molecules having an antigen binding fragment that immunospecifically binds to BTN1A1, such as anti-BTN1A1 antibodies. These molecules include those having an antigen binding fragment that immunospecifically binds to glycosylated BTN1A1, such as anti-glycosylated BTN1A1 antibodies. Also included are molecules having an antigen binding fragment that immunospecifically bind to BTN1A1 dimers, such as anti-BTN1A1 dimer antibodies. Also provided are methods for treating anti-PD-1 therapy or anti-PD-L1 therapy resistant or refractory cancers.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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