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Medicinal forms of phospholipid preparations and methods for their preparation
专利权人:
Vasiliy Fedorovich Uchaikin;Olga Mikhailovna Ipatova;Alexandr Ivanovich Archakov;Mariya Kirillovna Guseva;Elena Georgievna Tikhonova
发明人:
Alexandr Ivanovich Archakov,Mariya Kirillovna Guseva,Vasiliy Fedorovich Uchaikin,Elena Georgievna Tikhonova,Olga Mikhailovna Ipatova
申请号:
US12063581
公开号:
US08680061B2
申请日:
2006.08.11
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A method for producing a pharmaceutical composition comprising a combination of phospholipid and glycyrrhizic acid or a pharmaceutically acceptable salt thereof, which composition is hydratable to produce an injectable medicinal form, said method comprising subjecting a mixture of phospholipid and an aqueous solution of glycyrrhizic acid or a pharmaceutically acceptable salt thereof and a carbohydrate to homogenization, for example at 800-1200 bar pressure at a temperature of less than 90° C., and subjecting the product of the homogenization to a sublimation drying step to produce said composition. Compositions obtainable using this method, and hydrated forms of these ready for administration by injection form further aspects of the invention.
来源网站:
中国工程科技知识中心
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