A fluid transfer device may include a fluid transfer tip that has a tapered friction fitting for a corresponding hub and an additional means for gripping a hub in a locked position when connected to the fluid transfer tip by the friction fitting. A disconnecting member is provided with a resilient bias that causes it to engage the gripping means and thereby assist in holding the hub in the locked position. The disconnecting member is moveable relative to the fluid transfer tip and against the resilient bias so as to release engagement of the gripping means, move the hub out of the locked position provided by the gripping means and release the hub from the friction fitting.