The anticancer activity of thymol and carvacrol desired compounds has been invented, in order to obtain potent and cost effective molecule using in vitro cytotoxicity assay. The invention particularly relates to the thymol based molecules i.e. /- phenylacrylophenones represented by structure 1, possessing anticancer activity against human cancer cell lines. The compound also exhibited tubulin polymerisation inhibition. (£)-3-(4-hydroxy-5-isopropyl-2-methylphenyl)-l-(4- hydroxyphenyl)prop-2-en-l-one (2) and (£)-l-(3-hydroxy-4-methoxyphenyl)-3-(5-isopropyl-4- methoxy-2-methylphenyl)prop-2-en-l-one (4) , possessing molecular formula as CIoC C2iH24C>4j were synthesized from thymol, exhibit potent in-vitro anticancer activity.
